Hi, can anyone suggest an antidepressant that works for them? I’ve tried all sorts but the only one that works for me is venlafaxine but I had to come off it as I get the worst night sweats and they were destroying my sleep. I am now currently on clomipramine but this only helps with my OCD symptoms and doesn’t do much for my depression or anxiety. SSRIs don’t seem to work on me. Anyone found one that works for them?
The truth is what works for one person won’t for another. There are some people that anti-depressants just don’t really work well on, me being one. The issue is that depression caused by a situation or circumstances can’t really be treated with medication, whereas chemical imbalances in the brain, the likes of serotonin, neuroadrenalin etc etc are where anti-depressants work best, so if they aren’t working for you, you might want to consider alternative approaches such as cbt, talk therapy and lifestyle changes. That’s what I found to be more effective. (I was previously on Sertraline 200mg, then got switched out to Mirtazapine 45mg then fluloxatine but I had a hellish time with the last one). On a side note, I did find pregabalin good for anxiety but doctors are becoming less willing to prescribe this now. It’s not an anti-depressant, nor is it specifically designed for anxiety - rather it’s side effects proved good for people with anxiety.
Hi, I have never used them but know some people that have. They said that they made them feel more level-headed and emotionless but ultimately they stopped taking them. I have been told a lot that it is best to avoid them if you can as they only lead to more problems. Personally for me, the list of side effects was too much. I think you should speak to your GP to the best advice although I am slightly sceptical of them in case they just want to prescribe unneccesarily for pharma profits
Hi - Have to agree with Anthony on the fact that it's usually a system of trial and error in finding the one or combination that works best for the individual person. I never dreamed I would even be on any medication, as I was so anti ALL meds once. BUT, something happened to change all that and it was completely out of the blue, and basically something that someone did to affect me beyond anything I could have imagined. So, I was affected enough to finally speak to a GP, and she put me on Prozac, which has taken away all my anxiety and any depression I'd been feeling. It's honestly made a massive difference! There were side effects, but it's made my life livable again.
Ive been on quite a few, my body seems sensitive to medication. I'm trying to manage wihout. I have this woman whos meant to help me and its a text service at the moment but whenever i say i'm feeling a bit down the 1st thing she says is call the gp for tablets! which i refuse to do as ive been on them for years and finally off of them
I can understand your wanting to tackle the problem without meds, and kudos for that. Sometimes, just finding the right person(or therapist) to talk to, can make a difference. Depends how long you’ve been dealing with depression, how severe it is, and whether or not your body is resistant to the meds you’ve tried. It might be that you simply need a break from the usual stresses of life for a bit(eg stop the lift, I wanna get off!) :) Either way, your body and mind are telling you that something’s not right, and needs addressing. Maybe, you could initiate change via a new hobby ... one that involves relaxation. Unfortunately, anxiety is the dominant emotion in ASD, and if we aren’t given enough time to function on auto-pilot, our systems tend to be oushed into overdrive easily. This can cause secondary conditions such as OCD. Have you ever been able to manage your OCD and bring it under control, or has it remained a problem throughout your life for a long time?(if it’s okay to ask)
Ok .. golly this is a 'bare all' kind of chat space isn't it .......
.. I had six months off work some 20 years ago with what was diagnosed as clinical depression .. I now see it as a symptom of being ASD/AS
.. I started off being resistant to the idea of meds .. eventually I realised I had to do something different because I just wasn't functioning - at work or elsewhere
.. the GP tried a bunch of different things .. starting with Amytriptyline !! which turned me into a grinning zombie who slept most of the time :-) .. fifth try lucky and finally onto Fluoxetine (Prozac) .. which suits me down to the ground
.. I function fine .. I have ups and downs but no major peaks or troughs .. I enjoy life again
.. I've had a couple of goes at coming off the meds .. each time I descended into a black swamp
.. so now I just accept I'm on a minimal dose for the foreseeable future .. and I'm ok with that ..
I think SSRIs (like fluoxetine), SNRIs (like venlafaxine or clomipramine) and NARIs (like reboxetine) do have noticeably different effects, and they're different again from dopamine agonists. If you find one from one class unhelpful, it would seem logical to try a different a different class. You can find some drug info on Wikipedia or in the BNF, and maybe send or take that to your GP.
Well, that's a theory. In practice, for me, no drug (out of 6 or 7) has worked. Systemic psychotherapy helped a bit.
I take escitalopram, it did take about two months to be really effective.
its not a solution, antidepressant are for short term use, prolonged use is actual incredible harmful and can become dangerous. especially if their given to any under the age 30 as most people brains still keep developing way in to their 20s and premiant changes chemical imbalances in the brain forever. .
all anti depressants do for most autistic people is stop them functioning and that why we seem more normal or less fustrated by neurotypical because we cant think and are sedated.
Same experience here with escitalopram.
I now see things in a very different way. I look for means to cooperate rather than passive aggressive sabotage.
Initially there was a bit of weight gain, but with the lockdown I got that under control, burpees, and only eating when I'm hungry.
I see it as the lesser of two not so wonderful options... and every day you enjoy life again, is an extra day of pure profit...