Bad meltdowns before illness

Hi was wondering if anyone has experience with having issues the week before becoming sick

 My 6yo probably autistic kid tends to have a horrendously off week out of nowhere where he gets extremely emotional suddenly and any small thing sets him off into a huge tantrum/meltdown, and then he lashes out at school too. Almost always this out of nowhere behaviour ends in a fever, chest infection, ear infection etc, and then a completely different boy at the end of it. 

Wondered if anyone else noticed this in themselves or their kids and have any advice on managing it?

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