More challenging with age

Has anyone experienced life feeling more difficult as they get into their 30s and 40s?

I think someone posted a link a while ago to a paper on this but I lost the tab (I usually keep dozens open) and can't find the conversation again.

I can't put my finger on why. Are symptoms getting worse or am I just less willing to comply with the way things "should be done". I find myself increasingly impatient with my partner and using the phrase "you should understand me by now" or "you should know this by now". I feel like I can just no longer be the one to put my energy into things. Why should I be making such a huge effort all the time for other people's lives to be so easy. 

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