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Research into pre-natal causes of autism

scienceobservation

Hi. I'm a mum of three. We don't have autism in our family, but my third son showed many of the signs at aged 3: poor eye contact, lack of vocal recognition, biting, slow to learn and write. Luckily, with loving parents and teachers he developed wonderfully and made a loving group of friends. I have always been interested in autism as a mum in the community and have friends with children who have autism. I am also interested in scientific observation and thought - but definitely not speculation or unscientific causation. I understand autism is a neurodevelopmental disorder to do with brain systems and is spectral in range. I think that research should be directed to prenatal influences in the uterus - interesting research might be: raised CRP levels in mother are a sign that the body is undergoing response to inflammation due to virus/bacteria and increase CRP = autism in babies; Fifth disease B19 Paravovirus in mothers linked with prenatal fetal anaemia causing intercerebal hemorrhage. I also find interesting the link that austic children also have a higher prevalance of leaky gut syndrome and this is also connected to B19 virus and gut microbiota. There is also a link between PLEVA virus and B19 in older children, with PLEVA being more prevalant in boys. In summary, these are merely observations and things I have read up on in respected scientific jounals and papers as an interested mum with an active brain! Could our increasingly sterile modern environment coupled with the skewed increase in prescription of antibiotics have alters gut microbiota and decreased our resistance to B19 causing a rise in prenatal infection and brain damage shown in the rise in cases of autism worldwide? The brain-skin-gut connection has been thrown into the spotlight recently, particularly in relation to depression and mental health. I hope scientists can pull in funding to research properly these links thoroughly because somewhere in this lies the answer to the causes of autism. If we can develop a vaccine to protect mums-to-be against B19 and understand better prenatal brain damage which causes the brain to enlarge, then we could be on the right track.

Parents
  • Former Member
    Former Member

    scienceobservation said:

    Hi. I'm a mum of three. We don't have autism in our family,

    Is that a fact or an assumption? Have all of the ancestors of this child been scientifically tested? Can we have some evidence based discussion please? Nobody was aware of autism in my family until I got diagnosed at 56. Then, when I looked back and talked to relatives, it became clear that some of the eccentric behaviour that was a 'feature' of my father's family fitted very well with autism.

    but my third son showed many of the signs at aged 3: poor eye contact, lack of vocal recognition, biting, slow to learn and write. Luckily, with loving parents and teachers he developed wonderfully and made a loving group of friends.

    So, does he actually have a diagnosis or was he just different to his siblings? You make it sound as though he has "recovered" rather than having learnt some strategies for coping.

    If you are a good scientist then you will be wary of "confirmation bias" and the subjectivity of a parent's view of their own child. It sounds as though you have been looking for something and then used any evidence you have looked for to confirm your fears. That isn't scientific!

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  • Former Member
    Former Member

    scienceobservation said:

    Hi. I'm a mum of three. We don't have autism in our family,

    Is that a fact or an assumption? Have all of the ancestors of this child been scientifically tested? Can we have some evidence based discussion please? Nobody was aware of autism in my family until I got diagnosed at 56. Then, when I looked back and talked to relatives, it became clear that some of the eccentric behaviour that was a 'feature' of my father's family fitted very well with autism.

    but my third son showed many of the signs at aged 3: poor eye contact, lack of vocal recognition, biting, slow to learn and write. Luckily, with loving parents and teachers he developed wonderfully and made a loving group of friends.

    So, does he actually have a diagnosis or was he just different to his siblings? You make it sound as though he has "recovered" rather than having learnt some strategies for coping.

    If you are a good scientist then you will be wary of "confirmation bias" and the subjectivity of a parent's view of their own child. It sounds as though you have been looking for something and then used any evidence you have looked for to confirm your fears. That isn't scientific!

Children
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