My mouse don’t look me in the eye no more....

Autism symptoms replicated in mice after faecal transplants

Study aims to discover whether gut microbes play a part in development of the condition

Scientists have induced the hallmarks of autism in mice by giving them faecal transplants from humans with the condition.

The experiments were designed to test whether the communities of gut microbes found in people with autism have a role in their symptoms, an idea that is gaining ground among researchers.

In the study, animals that had faecal transplants from children with autism became less sociable, less vocal and developed repetitive behaviours. In contrast, genetically identical mice that had transplants from people without autism were unaffected by the procedure.

https://www.theguardian.com/society/2019/may/30/autism-symptoms-replicated-mice-after-faecal-transplants

Mice that had transplants from children with autism did not wrestle, push and sniff other mice as much as the control group of mice, which had transplants from people without autism. Nor did they produce as many ultrasonic squeaks. And while control mice might bury one or two marbles and then move on, mice with autism-related microbiomes kept going, an indication of repetitive behaviour.”

 

Parents
  • BUMP. Interestng little thread. Second time I've come across this concept, the last time was an article I included (which many poo-poohed) that suggested Autism is gut biome related.

    In the article I found they claimed to have CURED Autism by fecal transplant...

    My question is:

    How much of my crap do I need to make a NT eat, to make them more like me? 

    Fancy a crhocolate, anyone?

  • Erm, I think such a transplant goes up, not down, to try and put it delicately! Unless it's in a capsule which won't dissolve until it reaches the right point. Otherwise it would be destroyed by stomach acid.

Reply
  • Erm, I think such a transplant goes up, not down, to try and put it delicately! Unless it's in a capsule which won't dissolve until it reaches the right point. Otherwise it would be destroyed by stomach acid.

Children
  • In the coming autistic uprising it's gonna get messy!

    Is it gonna be like invasion of the body snatchers, where we go out at night in teams armed with turkey basters full of doo-doo, instead of those big pod things?