Please my son is 16 and Autistic is there anyone with a son of similar age that is going through a hard time and acting out as a result?? Finding it hard to cope

My son is 16 Autistic and Dyspraxic and is currently suffering from depression. 

He has totally changed since the depression came along. He is having therapy but dealing with his frustration with how he feels so hard. He has become so cruel and nasty. Me and my partner get told to f**k off, go f**k yourself, shut the f**k up, not to mention all the nasty way he speaks full stop. We can't speak to him unless he has an interest that takes his focus then he will engage. 

Then it is back to the nastiness again. The picture is way bigger than this but I just wondered if anyone is dealing with a teen son who isn’t nice to them and how they cope with it. When we try and talk to him he just says he doesn't want to be nasty but do we not get he is depressed!! He doesn't understand that just because he is feeling depressed that it means we don't have to put up with it. 

At a loss and can't cope anymore Sob