son 21 asperger surviveing a brakeup?

hi, any advise would be a real help, my son is 21 with asperger, his first ever seriouse relationship had just finnished and hes devastated, i dont know what to do or say to help him cope, hes not eating drinking sleeping or looking after himself, he says he cant cope and feels life is over and cant go on, on an emotional roller coaster, frustration and anger managment is an ongoing problem already, any ideas ?