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Irritable bowel syndrome and Amitriptyline

Kate Kestrel

Hi everyone,

has anyone on here been prescribed low dose Amitriptyline for Irritable Bowel Syndrome- and if so - did it help at all?

A family member of mine (who is also autistic) has had long standing issues with digestive problems and a consultant has prescribed this for them. They’ve been taking PPIs for ages but haven’t helped much (in fact I sometimes wonder if they’ve made things worse in the long run). 

If anyone else has tried Amitriptyline for this issue (or for any reason) I’d appreciate any insights into whether or not it’s been helpful to anyone. 

thanks :) 

Parents

  • I had to take Amitriptyline for migraines in the past, but hated it, made me feel like someone had poured me full of cement, was so tired, couldnt think, could barely move, so difficult to do anything that I just cried. I then decided to stop it without tapering, very bad idea, nonstop panic attacks, resting heart rate of about 150, sweating, horrid thing. But then again, my mum takes them to help her sleep (1 at night) and she doesnt have an issue (except a slight med hangover in the morning), so all people react differently, but for me it was one of the worst medicine experiences I have had.

  • in reply to Starfox

    Thank you Starfox - that’s really helpful to know. It’s so strange how people can have such different reactions to the same drug. It’s so helpful to hear of both experiences though - as it’s helpful to be prepared for what my family member might experience. I must confess I’m very worried about them taking this drug - but I want to be prepared so that I can be supportive if something like this happens. Knowledge is power isn’t it? Almost anyway! Better than having no idea what to expect at all. 
    I’m sorry about your experience - it sounds dreadful and must have been awful for you. Many years ago I had a really terrible reaction to an anti-depressant and I will never ever forget it - 2nd worse experience of my life. I think this is why I’m so wary of my relative taking this. I definitely wouldn’t dare take it. But because they’ve struggled so much with their digestive troubles I think they’re pretty desperate at this point. 
    so I’ll just have to keep my fingers crossed for them. 
    thanks so much for your help - and I’m glad it’s helping your mum :) 

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  • in reply to Starfox

    Thank you Starfox - that’s really helpful to know. It’s so strange how people can have such different reactions to the same drug. It’s so helpful to hear of both experiences though - as it’s helpful to be prepared for what my family member might experience. I must confess I’m very worried about them taking this drug - but I want to be prepared so that I can be supportive if something like this happens. Knowledge is power isn’t it? Almost anyway! Better than having no idea what to expect at all. 
    I’m sorry about your experience - it sounds dreadful and must have been awful for you. Many years ago I had a really terrible reaction to an anti-depressant and I will never ever forget it - 2nd worse experience of my life. I think this is why I’m so wary of my relative taking this. I definitely wouldn’t dare take it. But because they’ve struggled so much with their digestive troubles I think they’re pretty desperate at this point. 
    so I’ll just have to keep my fingers crossed for them. 
    thanks so much for your help - and I’m glad it’s helping your mum :) 

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