Irritable bowel syndrome and Amitriptyline

Hi everyone,

has anyone on here been prescribed low dose Amitriptyline for Irritable Bowel Syndrome- and if so - did it help at all?

A family member of mine (who is also autistic) has had long standing issues with digestive problems and a consultant has prescribed this for them. They’ve been taking PPIs for ages but haven’t helped much (in fact I sometimes wonder if they’ve made things worse in the long run). 

If anyone else has tried Amitriptyline for this issue (or for any reason) I’d appreciate any insights into whether or not it’s been helpful to anyone. 

thanks :) 

Parents
  • Hello Kate. Good to see you hear again, I came back today.

    I've got IBS and took Amitriptyline. I found it unhelpful. The side effects took their toll and I felt terrible, it made me worse. A lot worse. I had bad side effects but the IBS became severe after. It was a bad move. 

    I've read before that IBS medication often don't work and make it worse. I'm inclined to agree with this, at least for me. 

    Sorry I can't be of more help Kate. I hope it starts to work or you can find something else. 

    Katy x.

Reply
  • Hello Kate. Good to see you hear again, I came back today.

    I've got IBS and took Amitriptyline. I found it unhelpful. The side effects took their toll and I felt terrible, it made me worse. A lot worse. I had bad side effects but the IBS became severe after. It was a bad move. 

    I've read before that IBS medication often don't work and make it worse. I'm inclined to agree with this, at least for me. 

    Sorry I can't be of more help Kate. I hope it starts to work or you can find something else. 

    Katy x.

Children
  • Thanks Katy. I’m sorry it was not helpful for you - and it’s awful that it made your symptoms worse. That’s the last thing my relative needs as they’re already having such a tough time with their health. I was really worried when I looked at the side effects of Amytriptyline online. Bit scary. 
    Your experience is what I’ve been worrying about to be honest. Generally (for myself) I prefer more natural treatments whenever possible - but my relative is feeling pretty desperate to get help with this (understandably) and I think they’re going to take this drug.

    thanks for sharing you’re experience - I shall be prepared to offer support to them if they have a similar experience. 
    I hope you’ve found something that helps Katy?
    Thanks for your help - I so appreciate it! x