Irritable bowel syndrome and Amitriptyline

Hi everyone,

has anyone on here been prescribed low dose Amitriptyline for Irritable Bowel Syndrome- and if so - did it help at all?

A family member of mine (who is also autistic) has had long standing issues with digestive problems and a consultant has prescribed this for them. They’ve been taking PPIs for ages but haven’t helped much (in fact I sometimes wonder if they’ve made things worse in the long run). 

If anyone else has tried Amitriptyline for this issue (or for any reason) I’d appreciate any insights into whether or not it’s been helpful to anyone. 

thanks :) 

Parents
  • Hi, nice to hear from you. I don’t have any answers but my wife was a gastro nurse specialist for 15 years, she’s now a District Nurse, I won’t see her till tonight, she suffers from the same complaint, I will ask her opinion and get back to you.

  • Hi Roy - that’s really kind of you - and much appreciated! 
    There seems to be some kind of link between autism and gastro issues that I’ve never really fully understood. My family member’s consultant mentioned something called the ‘gut brain axis’. At first they thought it was Crohns but now they think not. They really need some help though as the symptoms are really difficult and affect their day to day life quite a lot. 
    Anyway - this community is always a good source of advice, info & understanding - I find that with so many things  that are (or might be) autism related. 

    I’d definitely welcome your wife’s thoughts on this if she wouldn’t mind sharing them - thank you! 

Reply
  • Hi Roy - that’s really kind of you - and much appreciated! 
    There seems to be some kind of link between autism and gastro issues that I’ve never really fully understood. My family member’s consultant mentioned something called the ‘gut brain axis’. At first they thought it was Crohns but now they think not. They really need some help though as the symptoms are really difficult and affect their day to day life quite a lot. 
    Anyway - this community is always a good source of advice, info & understanding - I find that with so many things  that are (or might be) autism related. 

    I’d definitely welcome your wife’s thoughts on this if she wouldn’t mind sharing them - thank you! 

Children
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