Is asd hereditary

Hi, I'm new to this page.

My 12 year old daughter is currently on the waiting list to be assessed for asd/adhd. It's very clear she has one or both. Thankfully the ep picked up the social communicator disorder amongst other things. 

Camhs have said it will be 18 months before a diagnosis so plan to hopefully go private. She has other ailments too. She's extremely great at masking alot of things. She cannot maintain friendships, has social, emotional and communication difficulties- hence the reason for the much needed assessment. 

I am curious to ask also if asd is hereditary? My brother has high functioning autism and adhd and sister is on the asd spectrum but she is still going through tests. They are on my dads side of the family. My partner has recently said that he notices that I am very meticulous and like to have things in order, have a routine, know what is happening ahead of things etc, and my stepmum asked me if I have ever been tested because of my brother and sister. I'm now overwhelmed if the chance of me having it is high and if so is it hereditary and my daughter has it because of me. 

Any help or advice would be appreciated. 

Parents
  • There is a large genetic component to autism. There seem to be two genetic systems at work. Firstly, there are many common genetic variations associated with autism, that occur in the population as a whole, and some of these appear to be beneficial - some are linked to higher than average educational achievement. The person with diagnosable autism just has a much higher concentration of these genetic variations than most of the population. The size of the individual variation tends to be small, relatively few base-pairs are affected in the case of each variant. Secondly, are rarer genetic variations, these can arise spontaneously, that is neither parent had them. These tend to be larger, such as duplication events or deletion events, where a length of DNA is  repeated, or it is removed completely. The autism caused by the rarer variations tends to be accompanied by more serious comorbidities, such as intellectual disability. Genetics is not the whole story, however, as environmental factors - such as a difficult birth -  can also contribute.

Reply
  • There is a large genetic component to autism. There seem to be two genetic systems at work. Firstly, there are many common genetic variations associated with autism, that occur in the population as a whole, and some of these appear to be beneficial - some are linked to higher than average educational achievement. The person with diagnosable autism just has a much higher concentration of these genetic variations than most of the population. The size of the individual variation tends to be small, relatively few base-pairs are affected in the case of each variant. Secondly, are rarer genetic variations, these can arise spontaneously, that is neither parent had them. These tend to be larger, such as duplication events or deletion events, where a length of DNA is  repeated, or it is removed completely. The autism caused by the rarer variations tends to be accompanied by more serious comorbidities, such as intellectual disability. Genetics is not the whole story, however, as environmental factors - such as a difficult birth -  can also contribute.

Children
  • Yes, people tend to assume its all about inheritance and some even worry about passing it on, buts not that simple.  Also, autism isn't a specific gene, its a combination of genes that might affect the brains development.   Inheritance can pass them on, but random genetic variations could also mean these occur without any autism history. Even if you have autism yourself, any children you have might not develop enough difficulties or difference to be diagnosed with autism, or they may be more affected.

    Differences in the brains development are usually in place before birth, but as the brain keeps developing after birth then yes environment factors can come into play - changes in the brains development due to stress or damage.  Gets complicated.

    Diagnosable autism is quite widespread, 1 in 100 people have a diagnosis but many more could probably be diagnosed but may not realise or want to, or able to.  The genes responsible are much more widespread.  People can say "we are all a bit autistic" or "we are all on the spectrum" and that is kind of true in the sense we can all have the odd difficulty here and there, but to be diagnosed with autism takes more than one or two difficulties, and usually in different areas.