Out there thinking - ASD/OCD is an autoimmune response to disease

PANDAS can see that autism can happen at any time, in response to an illness. This research paper goes further linking any immune stressor to physically changing the brain chemistry/biology to improve your chances at living. You actually avoid human contact and wash more often - on a subconscious level. Manifest as ASD and OCD and others.

You have seen the opposite in mice infected with a parasite, who seem more attracted to cats, - https://www.nature.com/news/parasite-makes-mice-lose-fear-of-cats-permanently-1.13777

"The results are novel, as this sensitive and comprehensive testing has revealed how prenatal and early postnatal immune activation may regulate core behavioral signs associated with ASD and certain other developmental disorders through changes in signal flow between different structural components of behavior-driving neural circuits," said Bolshakov. "These findings may be of a significant translational value, as they provide important clues to understanding the mechanisms of these disorders and potentially their treatment."

https://www.sciencedaily.com/releases/2018/03/180328083434.htm

Parents
  • Hmmmm......if ASD/OCD is an autoimmune response to disease, then shouldn't ASD/OCD prevalence rates be higher in regions that have more disease? But it doesn't seem that way? (that's what the nature article was saying about schizophrenia)

    I also agree with what Cloudy Mountains said, PANDAS is not autism. And you can't just 'catch' autism. One of ASD's diagnostic criteria is that the symptoms need to be present in childhood. But autoimmune disorders can happen at any time. So if they ask about whether a patient has had a recent infection when diagnosing autism, they are probably trying to rule out other explanations that are not autism. 

  • Hmmmm......if ASD/OCD is an autoimmune response to disease, then shouldn't ASD/OCD prevalence rates be higher in regions that have more disease? But it doesn't seem that way?

    Qwerty - the finding were from a peer-reviewed paper, published in a top journal.

    "McLean Hospital neuroscientists have found that immune system activation during pregnancy and right at birth can cause alterations in the brain's neural circuits during young adulthood that are consistent with behavioral symptoms common in autism spectrum disorder (ASD) and other developmental conditions. The detailed findings are available in the March 28, 2018, issue of the Journal of Neuroscience."

    As any scientist will know a collection of symptoms becomes a disorder when it's harmful. And that harm can simply be that they seem to function less than the people around them.

    Here are the high prevalence rates, when refugees are tested for autism. As they come from other countries - with perhaps more "disease".

    https://community.autism.org.uk/f/adults-on-the-autistic-spectrum/16071/an-outbreak-of-autism-amongst-refugees

    Disease is a complex situation, depending on age, blood type, and many other factors. As anyone who has had "deli belly" would agree. Why don't the locals seem to get it?

    I think if we try to educate people instead of shutting down discussion it might go along way to moving things along.

Reply
  • Hmmmm......if ASD/OCD is an autoimmune response to disease, then shouldn't ASD/OCD prevalence rates be higher in regions that have more disease? But it doesn't seem that way?

    Qwerty - the finding were from a peer-reviewed paper, published in a top journal.

    "McLean Hospital neuroscientists have found that immune system activation during pregnancy and right at birth can cause alterations in the brain's neural circuits during young adulthood that are consistent with behavioral symptoms common in autism spectrum disorder (ASD) and other developmental conditions. The detailed findings are available in the March 28, 2018, issue of the Journal of Neuroscience."

    As any scientist will know a collection of symptoms becomes a disorder when it's harmful. And that harm can simply be that they seem to function less than the people around them.

    Here are the high prevalence rates, when refugees are tested for autism. As they come from other countries - with perhaps more "disease".

    https://community.autism.org.uk/f/adults-on-the-autistic-spectrum/16071/an-outbreak-of-autism-amongst-refugees

    Disease is a complex situation, depending on age, blood type, and many other factors. As anyone who has had "deli belly" would agree. Why don't the locals seem to get it?

    I think if we try to educate people instead of shutting down discussion it might go along way to moving things along.

Children
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